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NCCIH Natural Product Early Phase Clinical Trial Award (R33 Clinical Trial Required)

Open now · Grant · PAR-25-270

Next cut-off
13 Nov '26
in 68 days
Call budget
$1.1M
across every grant here
Grants expected
,
not published for this call
Funding rate
,
not published, read the conditions

What this call funds

This Notice of Funding Opportunity (NOFO) encourages applications for investigator-initiated, early phase, clinical trials of natural products (i.e., botanicals, dietary supplements, and probiotics), which have a strong scientific premise to justify further clinical testing. For this NOFO, natural products include promising nutritional regimens that standardize the amount of a specific naturally occurring nutritional compound (e.g., omega-3 fatty acids, anthocyanidins, or polyphenols) and have compelling preliminary evidence. Under this NOFO, trials must be designed so that results, whether positive or negative, will provide information of high scientific utility and will support decisions about further development or testing of the natural product.

Trimmed here, the full scope, expected outcomes and award criteria are on the official topic page ↗.

What applying costs you

ItemEstimateNote
Drafting effort3–4 weekssingle submission
Time to first payment6–9 monthscut-off → evaluation → grant agreement

These are Bemzu's estimates from the call's structure (the number of stages and whether a consortium is required) not figures published by the Commission. Only the co-financing share is read from the call itself.

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