Home / US Department of Health and Human Services / PAR-25-374

Translational Bioinformatics and Experimental Approaches to Advance Drug Repositioning and Combination Therapy Development for Alzheimers Disease and Related Dementias (R01 Clinical Trial Not Allowed)

Open now · Grant · PAR-25-374

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Next cut-off

07 May '28

in 609 days

Call budget

$1.0M

across every grant here

Grants expected

not published for this call

Funding rate

not published, read the conditions

What this call funds

This Notice of Funding Opportunity (NOFO) invites applications that propose to use mouse models to conduct rigorous preclinical testing of drugs or drug combinations currently used for other conditions, as well as investigational drugs at various stages of clinical development, predicted to be efficacious in AD/ADRD. This initiative will also support preclinical testing of repurposable or investigational drug candidates in combination with non-pharmacologic interventions leading to robust translational outcomes. The central goal is to establish robust proof of concept that will enable rational drug repurposing and combination therapy development for the treatment and prevention of AD/ADRD.

What applying costs you

Item	Estimate	Note
Drafting effort	3–4 weeks	single submission
Time to first payment	6–9 months	cut-off → evaluation → grant agreement

These are Bemzu's estimates from the call's structure (the number of stages and whether a consortium is required) not figures published by the Commission. Only the co-financing share is read from the call itself.

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