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Discovery of in vivo Chemical Probes for the Nervous System (R01 Clinical Trial Not Allowed)

Open now · Grant · PAR-27-081

Next cut-off
05 Mar '27
in 180 days
Call budget
,
across every grant here
Grants expected
,
not published for this call
Funding rate
,
not published, read the conditions

What this call funds

The purpose of this Notice of Funding Opportunity (NOFO) is to support investigators who have the interest and capability to join efforts for the discovery of in vivo chemical probes for novel brain targets. It is expected that applicants will have, in hand, the starting compounds (validated hits) for chemical optimization and bioassays for testing new analog compounds.Through this NOFO, NIH wishes to stimulate research in:Discovery and development of novel, small molecules for their potential use in understanding biological processes relevant to the missions of National Institute of Mental Health (NIMH), National Institute on Drug Abuse (NIDA), National Eye Institute (NEI), and/or National Institute on Aging (NIA) andDiscovery and/or validation of novel, biological targets that will inform studies of brain disease mechanisms.Emphasis will be placed on projects that provide new insight into important disease-related biological targets and biological processes.

What applying costs you

ItemEstimateNote
Drafting effort3–4 weekssingle submission
Time to first payment6–9 monthscut-off → evaluation → grant agreement

These are Bemzu's estimates from the call's structure (the number of stages and whether a consortium is required) not figures published by the Commission. Only the co-financing share is read from the call itself.

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